Office: SC 446 / Phone: (859) 572-5408
The Daniels group engages in a combination of physical and analytical chemistry research that utilizes Capillary Electrophoresis and Capillary Electrochromatography to measure the kinetics and dynamics of small molecules within mobile phases and the solid/liquid interface when a stationary phase is present. By focusing on external stimuli responsive polymers, this research can be used to understand how small molecules interact with adaptive materials in efforts to engineer smarter technology.
Office: SC 447 / Phone: (859) 572-7543
Research in the Gemene group utilizes analytical chemistry techniques to develop electrochemical sensors that can be used in biomedical applications. Recent interests include the measurement of biomedically important polyions (e.g., heparin, protamine) and the detection of anions (e.g., chloride, bicarbonate) in challenging physiological samples.
Office: SC 445 / Phone: (859) 572-6552
Research in the Guy group focuses on the role of posttranscriptional tRNA modifications in eukaryotic cells where defects are often associated with diseases such as intellectual disability and cancer. The group uses a variety of biochemical, molecular biological, and genetic techniques to study proteins and nucleic acids to discover new aspects of tRNA biology.
The Hare group uses a variety of spectroscopic and computational techniques to study how molecules and light interact. Most of our research focuses on molecules of environmental interest, such as estrogens and pharmaceuticals.
Office: SC 451 / (859) 572-6188
The focus of the Hopper group is to monitor the changes in metabolites as crop plants are exposed to environmental stress. Metabolites are measured using mass spectrometry techniques. Also of interest is the development of devices used for monitoring environmental conditions, and building computational tools to better identify metabolites.
Office: SC 449 / (859) 572-7785
The Lagadic group deals with the development of functional hybrid organic-inorganic silicate-based nanomaterials, with applications as drug delivery systems (1), engineered polymer composites (2) and environmental adsorbents (3).
The Ma group is interested in the design and development of anticancer drug candidates with a special focus on anti-breast cancer drug discovery. A combination of modern techniques such as organic synthesis, biochemistry and computer modeling are utilized in our lab to investigate bioactive chemicals and drug molecules.
Office: SC 349 / (859) 572-5733
Research in the Onorato group encompasses organic synthesis, medicinal chemistry, and strong collaborations with biology and cardiovascular research. Our main focus is the synthesis of biologically relevant natural products and their analogues, with the long term goal of developing lead compounds for the treatment of invasive fungal infections and chronic inflammation.
The Russell Group studies the synthesis and characterization of dehydroheteroarylannulenes, compounds possessing benzene rings separated by carbon-carbon triple bonds. These compounds have unusual chemical and physical properties and are expected to be very important in the design and manufacture of nanoelectronics, such as molecule size wires, logic gates, and memory storage devices.