“After reading through numerous irrelevant abstracts, I began to get a little frustrated. I needed a new research strategy. So, I stepped back and started thinking about the bigger picture and predicting connections to guide my searches. ‘Okay, if I know that histidine dipeptides are antioxidants, then what pathways use antioxidants or play a role in cell toxicity?’ Through this strategy of questioning and predicting, my research progressed."